Scientific Focus
CLINICAL AND TRANSLATIONAL NEUROSCIENCE
Advanced MRI Methods (radiomics, metabolic imaging, qMRI)
Methods
• In and ex vivo (X-nuclei) MR-Spectroscopy
• In and ex vivo quantitative MRI and MR-Spectroscopy
• In and ex vivo Sodium MRI
Selected Publications
Thomas DC, Deichmann R, Nöth U, Langkammer C, Ferreira M, Golbach R, Hattingen E, Wenger KJ: A fast protocol for multicenter and multiparametric quantitative MRI studies in brain tumor patients using vendor sequences. NEURO-ONCOL ADV 2024
Alcicek S, Divé I, Thomas DC, Prinz V, Forster MT, Czabanka M, Weber KJ, Steinbach JP, Ronellenfitsch MW, Hattingen E, Pilatus U, Wenger KJ: 2D 1 H sLASER Long-TE and 3D 31 P Chemical Shift Imaging at 3 T for Monitoring Fasting-Induced Changes in Brain Tumor Tissue. J MAGN RESON IMAGING 2025
Alcicek S, Ronellenfitsch MW, Steinbach JP, Manzhurtsev A, Thomas DC, Weber KJ, Prinz V, Forster MT, Hattingen E, Pilatus U, Wenger KJ: Optimized Long-TE 1 H sLASER MR Spectroscopic Imaging at 3T for Separate Quantification of Glutamate and Glutamine in Glioma. J MAGN RESON IMAGING 2025
Acker F*, Wenger K*, Reck M, Waller C, Hoffknecht P, Bethge A, Nusch A, Reiser M, Bernhardt C, Bendel M, Lennartz C, Fleitz A, Jänicke M, Ludwig P, Groth A, Griesinger F, Thomas M, Eberhardt WEE, Sebastian M: Prediction of the Individual Risk for the Development of Brain Metastases in Patients with Non-Oncogene-Addicted Non-Small Cell Lung Cancer: Real-world data from the German Prospective CRISP Registry (AIO-TRK-0315). Int J Cancer. 2026
Alcicek S, Manzhurtsev A, Thomas DC, Divé I, Weber KJ, Prinz V, Jussen D, Deelchand DK, Oeltzschner G, Ronellenfitsch MW, Steinbach JP, Hattingen E, Pilatus U, Wenger KJ: In vivo characterization of the redox balance in IDH-wildtype gliomas: A J-difference edited MEGA-sLASER MRS study at 3 T. Cancer Metab. 2026

