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Prof. Dr. Elke Hattingen

Campus Niederrad
Institute for Neuroradiology
Goethe-University Frankfurt
Theodor-Stern-Kai 7
60590 Frankfurt

Germany

Tel.: 49 (0)69-6301-5463

E-Mail: hattingen@med.uni-frankfurt.de

Web

Scientific Focus

Our group is interested in metabolic and quantitative imaging of brain tumors, epilepsy, multiple sclerosis and cerebrovascular diseases. Future projects will focus on radionomics.

Methods

– quantitative MRI – T1, T2, T2*, T2′ relaxometry, magnetization transfer, chemical exchange staturation transfer (CEST)-imaging, diffusion tensor imaging (DTI), perfusion imaging
– MR spectroscopy (H1, P31)

Selected Publications

Arendt CT, Klinsing S, Becke E, Fahim M, Koepsell J, Jahnke K, Ronellenfitsch MW, Vehreschild MJ, Shrestha M, Deichmann R, Schüre JR, Hattingen E. Subacute Frontoinsular-Cingulate Tract Changes in Unvaccinated COVID-19 Survivors: a Tract-Based Spatial Statistics Study of Diffusion Tensor Imaging. Brain Res Bull. 2026 Jun 2:111986. doi: 10.1016/j.brainresbull.2026.111986.

Fahim M, Hattingen E, Jurcoane A, Schüre JR, Klinsing S, Koepsell J, Jahnke K, Ronellenfitsch MW, Pilatus U, Vehreschild MJGT, Deichmann R, Arendt CT. Impact on the microstructure of deep gray matter in unvaccinated patients after moderate-to-severe COVID-19: insights from MRI T1 mapping. Eur Radiol Exp. 2025 Jul 5;9(1):63. doi: 10.1186/s41747-025-00598-7.

Thomas DC, Deichmann R, Nöth U, Langkammer C, Ferreira M, Golbach R, Hattingen E, Wenger KJ. A fast protocol for multicenter and multiparametric quantitative MRI studies in brain tumor patients using vendor sequences. Neurooncol Adv. 2024 Jul 4;6(1):vdae117. doi: 10.1093/noajnl/vdae117.

Steidl E, Neuhaus E, Shrestha M, Deichmann R, Weber K, Steinbach JP, Pilatus U, Hattingen E, Schüre JR. Pathological tissue changes in brain tumors affect the pH-sensitivity of the T1-corrected apparent exchange dependent relaxation (AREX) of the amide protons. NMR Biomed. 2025 Jan;38(1):e5285. doi: 10.1002/nbm.5285.

Alcicek S, Pilatus U, Manzhurtsev A, Weber KJ, Ronellenfitsch MW, Steinbach JP, Hattingen E, Wenger KJ. Amino acid metabolism in glioma: in vivo MR- spectroscopic detection of alanine as a potential biomarker of poor survival in glioma patients. J Neurooncol. 2024 Nov;170(2):451-461. doi: 10.1007/s11060-024-04803-2.

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