Biostatistics, diagnostic and biomarker studies, randomized-controlled trials (phase-IIa, phase-III), brain stimulation and behavioural/psychotherapeutic interventions.

Luckhardt C, Schütz M, Mühlherr AM, Boxhoorn S, Ecker C, Mössinger H, Siemann J, Schlechter F, Castelo-Branco M, Pereira HC, Latinus M, Ricou C, Bonnet-Brilhault F, Salvador R, Ruffini G, Nowak R, Siniatchkin M, Dempfle A, Freitag CM. Transcranial Direct Current Stimulation of the Temporoparietal Junction in Autism Spectrum Disorder: Results of a Phase-IIa Randomized, Double-Blind, Sham-Controlled Feasibility Study. Autism Res. 2025 Sep;18(9):1861-1876. doi:10.1002/aur.70084. Epub 2025 Jul 16. PMID: 40665956; PMCID: PMC12442529.

Bast N, Polzer L, Raji N, Schnettler L, Kleber S, Lemler C, Kitzerow-Cleven J, Kim Z, Schaer M, Freitag CM. Early intervention increases reactive joint
attention in autistic preschoolers with arousal regulation as mediator. Eur Child Adolesc Psychiatry. 2025 Oct;34(10):3161-3174. doi:10.1007/s00787-025-02738-1. Epub 2025 May 10. PMID: 40347242; PMCID:
PMC12592278.

Freitag CM, Kirchner M, Sauer LD, Kleber SK, Polzer L, Raji N, Lemler C, Fröhlich U, Jarczok T, Geissler J, Radtke F, Ring M, Roessner V, Taurines R,
Noterdaeme M, Teufel K, Kim Z, Kitzerow-Cleven J. Complex, low-intensity, individualised naturalistic developmental behavioural intervention in toddlers
and pre-schoolers with autism spectrum disorder: The multicentre, observer-blind, parallel-group randomised-controlled A-FFIP trial. J Child Psychol Psychiatry. 2025 Oct;66(10):1500-1513. doi: 10.1111/jcpp.14162. Epub 2025 Mar 26. PMID: 40135359; PMCID: PMC12447682.

Mayer JS, Kohlhas L, Stermann J, Medda J, Brandt GA, Grimm O, Pawley AD, Asherson P, Sanchez JP, Richarte V, Bergsma D, Koch ED, Muntaner-Mas A, Ebner-Priemer UW, Kieser M, Retz W, Ortega FB, Colla M, Buitelaar JK, Kuntsi J, Ramos-Quiroga JA, Reif A, Freitag CM. Bright light therapy versus physical exercise to prevent co-occurring depression in adolescents and young adults with attention-deficit/hyperactivity disorder: a multicentre, three-arm, randomised controlled, pilot phase-IIa trial. Eur Arch Psychiatry Clin Neurosci. 2025 Apr;275(3):653-665. doi: 10.1007/s00406-024-01784-1. Epub 2024 Apr 16. PMID: 38627266; PMCID: PMC11946981.

Bernhard A, Ackermann K, Martinelli A, Chiocchetti AG, Vllasaliu L, González-Madruga K, Batchelor M, Raschle NM, Oldenhof H, Jansen LMC, Kohls G, Konrad K, Popma A, Stadler C, Fairchild G, Freitag CM. Neuroendocrine Stress Response in Female and Male Youths With Conduct Disorder and Associations With Early Adversity. J Am Acad Child Adolesc Psychiatry. 2022 May;61(5):698-710. doi: 10.1016/j.jaac.2021.11.023. Epub 2021 Nov 29. PMID: 34856340.