Prof. Dr. Erin M. Schuman
Max Planck Institute for Brain Research
Max von Laue Strasse 4
60438 Frankfurt am Main
Tel 0049 69 850033-1000
E-Mail: erin.schuman@brain.mpg.de
Scientific Focus
cell biology of neurons; protein synthesis and degradation; mechanisms of information storage in the brain; synaptic plasticity; learning and memory
Methods
molecular biology, biochemistry, imaging, electrophysiology, proteomics, bioinformatics
Selected Publications
Van Oostrum, M., Blok, T., Giandomenico, S.L., tom Dieck, S., Tushev, G., Fürst, N., Langer, J., and Schuman, E.M. (2023). The proteomic landscape of synaptic diversity across brain regions and cell types. Cell, 186, 1-17. https://doi.org/10.1016/j.cell.2023.09.028
Sun, C., Desch, K., Nassim-Assir, B., Giandomenico, S.L., Nemcova, P., Langer, J.D., and Schuman, E.M. (2023). An abundance of free regulatory (19 S) proteasome particles regulates neuronal synapses. Science380, 811. doi: 10.1126/science.adf2018
Glock, C. Biever, A., Nassim Azir, B., Kao, A., Bartnik, I., tom Dieck, S., and Schuman, E.M. (2021). The translatome of neuronal cell bodies, dendrites and axons. PNAS, 118 (43), e2113929118; doi: 10.1073/pnas.2113929118.
Biever, A., Glock, C., Tushev, G., Ciirdaeva, E., Dalmay, T., Langer, J.T. and Schuman, E.M. (2020). Monosomes actively translate synaptic mRNAs in neuronal processes. Science, 367 (6477), eaay 4991, doi: 10.1126/science.aay4991.
Hafner, A.S., Donlin-Asp, P.G., Leitch, B., Herzog, E., and Schuman, E.M. (2019). Local protein synthesis is a ubiquitous feature of neuronal pre- and postsynaptic compartments. Science, 364, (6441), 650. doi: 10.1126/science.aau3644.