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Prof. Dr. Peter Jedlicka

Professorship for Computer-Based Modelling
in the field of 3R Animal Protection
Faculty of Medicine

NeuroScience Center
Clinical Neuroanatomy (Anatomy I)
Theodor-Stern-Kai 7
D-60590 Frankfurt am Main

+49 179 238 6269




Scientific Focus

Computerbasiertes Modelling im 3R Tierschutz, Computational neuroscience/Theoretische Neurowissenschaft, Neurobiologie




Compartmental modeling (NEURON), morphological modeling (TREES toolbox), stochastic reaction-diffusion modeling (STEPS, MCell)

Extracellular field recordings (e.g. LTP measurements) in the dentate gyrus in vivo

Intracellular patch-clamp recordings in acutely isolated brain slices and organotypical slice cultures Immunohistochemistry




Selected Publications

Ebner C, Clopath C, Jedlicka P*, Cuntz H* (2019) Unifying Long-Term Plasticity Rules for Excitatory Synapses by Modeling Dendrites of Cortical Pyramidal Neurons, Cell Reports, 29:4295-4307, Impact Factor 7.8


Jungenitz T, Beining M, Radic T, Deller T, Cuntz H, Jedlicka P*, Schwarzacher SWS* (2018) Structural homo- and heterosynaptic plasticity in mature and adult newborn rat hippocampal granule cells. PNAS, 115:E4670-E4679, Impact factor 9.7


Beining M, Mongiat L, Schwarzacher SW, Cuntz H*, Jedlicka P* (2017) T2N as a new tool for robust electrophysiological modeling demonstrated for mature and adult-born dentate granule cells. eLife, 6, e26517, Impact factor 7.7


Jedlicka P, Benuskova L, Abraham WC (2015) A voltage-based STDP rule combined with fast BCMlike metaplasticity accounts for LTP and concurrent “heterosynaptic” LTD in the dentate gyrus in vivo. PLOS Computational Biology, 11:e1004588, Impact Factor 4.6


Jedlicka P, Hoon M, Papadopoulos T, Vlachos A, Winkels R, Poulopoulos A, Betz H, Deller T, Brose N, Varoqueaux F, Schwarzacher SW (2011) Increased dentate gyrus excitability in neuroligin-2-deficient mice in vivo. Cerebral Cortex, 21:357-367, Impact Factor 6.5

* Geteilte Autorenschaft

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