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apl. Prof. Dr. Erik Maronde

Campus Niederrad
Goethe-Universität Frankfurt
Inst. für Zelluläre und Molekulare Anatomie
60590 Frankfurt am Main

Tel.: 49 (0)69-6301-7770


Scientific Focus

My scientific focus mostly covers three subfields of chronobiology, first the timing of neuronal signal transduction processes, second the phenotypes of “clock gene”, namely period-gene knockout mice and the role of the pineal gland and melatonin in physiological processes and selected clinical phenotypes like the “autism spectrum”.



Neuronal cell culture, reporter gene assays, Western Blot, immunocytochemistry, immunoprecipitation, ELISA, genomics (data analysis only), proteomics (data analysis only), histology including micro-CT, mouse behavioral tests including ultrasonic vocalization recording and analysis


Selected Publications

Maronde E, Schilling AF, Seitz S, Schinke T, Schmutz I, van der Horst G, Amling M, Albrecht U. The clock genes Period 2 and Cryptochrome 2 differentially balance bone formation. PLoS One. 2010 Jul 12;5(7):e11527. doi: 10.1371/journal.pone.0011527. PubMed PMID: 20634945; PubMed Central PMCID: PMC2902506.

Bechstein P, Rehbach NJ, Yuhasingham G, Schürmann C, Göpfert M, Kössl M, Maronde E. The clock gene Period1 regulates innate routine behaviour in mice. Proc Biol Sci. 2014 Mar 5;281(1781):20140034. doi: 10.1098/rspb.2014.0034. Print 2014 Apr 22. Erratum in: Proc Biol Sci. 2014 Nov 22;281(1795). doi:10.1098/rspb.2014.0784. PubMed PMID: 24598427; PubMed Central PMCID: PMC3953852.

Benabou M, Rolland T, Leblond CS, Millot GA, Huguet G, Delorme R, Leboyer M, Pagan C, Callebert J, Maronde E, Bourgeron T. Heritability of the melatonin synthesis variability in autism spectrum disorders. Sci Rep. 2017 Dec 18;7(1):17746. doi: 10.1038/s41598-017-18016-3. PubMed PMID: 29255243; PubMed Central PMCID: PMC5735101.

Maronde E. Trehalose Activates CRE-Dependent Transcriptional Signaling in HT22 Mouse Hippocampal Neuronal Cells: A Central Role for PKA Without cAMP Elevation. Front Mol Neurosci. 2018 Oct 22;11:386. doi: 10.3389/fnmol.2018.00386. eCollection 2018. PubMed PMID: 30405349; PubMed Central PMCID: PMC6204353.

Bahlmann O, Schürmann C, Maronde E. Altered laryngeal morphology in Period1 deficient mice. Ann Anat. 2019 Feb 1;223:43-48. doi: 10.1016/j.aanat.2019.01.009. [Epub ahead of print] PubMed PMID: 30716467.

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