Prof. Dr. Manfred Kössl

Institute for Cell Biology and Neuroscience
Faculty of Biosciences
Siesmayerstr. 70 A
D-60323 Frankfurt /Main

Tel 069-79824761
Fax 069-34750

koesslbio.uni-frankfurt.de

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Scientific Focus

· Physiology and biomechanics of auditory organs in mammals and insects.
· Focus: role of auditory motor proteins in generation of high sensitivity and fine frequency resolution of hearing
· Neuronal feedback and neuromodulation in auditory midbrain, thalamus and cortex
· Developmental plasticity of the auditory cortex. Focus: developmental emergence of echo-delay sensitive neurons and cortical chronotopicity in echolocating bats
· Role of attention in processing of auditory objects in rodents and human.
· Vibration sensors in spiders.

Methods

In vivo and in vitro electrophysiology, multiple electrode recordings. neuropharmacolocical methods, bioacoustic methods, laser-interferometry, measurement of otoacoustic emissions, human psychophysics, neuroanatomical and immunohistochemical methods

Animal models: rodents, bats, insects, spiders, humans

Selected Publications

Russell IJ Drexl M Foeller E Vater M Kössl M (2003a). Synchronization of a non-linear oscillator: Processing of the CF component of the echo-response signal in the cochlea of the mustached bat. J Neuroscience 23:9508-9518.

Russell IJ Drexl M Foeller E Vater M Kössl M (2003b) The development of a single frequency place in the mammalian cochlea: The cochlear resonance in the mustached bat Pteronotus parnellii. J Neuroscience 23:10971-10981.

Kössl M Foeller E Drexl M Vater M Mora E Coro E Russell IJ (2003). Postnatal development of cochlear function in the mustached bat, Pteronotus parnellii. J Neurophysiology 90:2261-2273.

Mora EC Kössl M (2004) Ambiguities in sound duration selectivity by neurons in the inferior colliculus of the bat Molossus molossus from Cuba. J Neurophysiol 91:2215-2226.

Wittekindt A Drexl M Kössl M (2005) Cochlear Sensitivity in the lesser spear-nosed bat, Phyllostomus discolor. J Comp Physiol A 191: 31–36

Gaese, B.H., King, I., Felsheim, C., Ostwald, J and von der Behrens, W. (2006) Discrimination of direction in fast frequency-modulated tones by rats. J Assoc Res Otolaryngol 7: 48-58

Macias S Mora EC Coro F Kössl M (2006)Threshold minima and maxima in the behavioral audiograms of the bats Artibeus jamaicensis and Eptesicus fuscus are not produced by cochlear mechanics. Hearing Research 212: 245–250

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